Article
The NRF2 readout beyond genotyping†.
The Journal of pathology - 1 Jul 2026
Suzuki Yukako, Ge Maolin
Abstract excerpt
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer mortality, and many patients derive limited benefit from current systemic therapies. Until now, clinical and translational efforts have largely focused on recurrent genomic alterations in the Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (NRF2) axis, yet mutation status alone often fails to capture the...
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