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Article

Identification of STMN1 as a lactylation‑related driver of lung cancer progression using Mendelian randomization.

Molecular medicine reports - 1 May 2026

Cai Yifan, Zhong Yucheng, Wang Honglin, Zhu Shuang, Huang Fang, Zhang Qiuyue, Hu Shaobo

Abstract excerpt

Lung cancer is an aggressive malignancy associated with a rapid progression and poor prognosis, for which immunotherapy only exhibits modest efficacy in most patients. In lung cancer, high lactate is associated with a low immunotherapy response and shortened survival; however, causal lactylation‑related genes remain to be elucidated. In the present study, candidate genes were screened using Mendelian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41930463
DOI: 10.3892/mmr.2026.13866
PMCID: PMC13051255

Genes

STMN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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