Back to search

Article

Identification of tumor antigens and immune subtypes of early-stage lung squamous cell carcinoma for mRNA vaccine development

2022-11-02

Abstract excerpt

In lung squamous cell carcinoma (LUSC), current mRNA vaccines show promising effect, despite lack of benefit for a large number of patients. We categorized the ideal population for mRNA vaccines and explored available targets. Leucine-rich repeat LGI family member 2 (LGI2), amine oxidase copper containing 1 (AOC1), periostin (POSTN), and collagen type V alpha 2 (COL5A2) were discovered using mutation, survival and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9924e4a9-c787-5f4d-b697-d44b260b45f0
DOI
10.21203/rs.3.rs-2219061/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of tumor antigens and immune subtypes of early-stage lung squamous cell carcinoma for mRNA vaccine developmentDOI 10.21203/rs.3.rs-2219061/v1
Identifying novel tumor-related antigens and immune phenotypes for developing mRNA vaccines in lung adenocarcinoma.Semantic proximity
A Novel Immune-Related Seventeen-Gene Signature for Predicting Early Stage Lung Squamous Cell Carcinoma PrognosisSemantic proximity
The tumor environment immune phenotype of LUSC by genome-wide analysis.Semantic proximity
Single-cell RNA sequencing reveals potential therapeutic targets in the tumor microenvironment of lung squamous cell carcinomaSemantic proximity
The tumor environment immune phenotype of LUSC by genome-wide analysisSemantic proximity
Development and validation of a novel immune-related prognostic signature in lung squamous cell carcinoma patientsSemantic proximity
Integrated analysis of single-cell and bulk RNA-sequencing identifies a signature based on T-cell marker genes to predict prognosis and therapeutic response in lung squamous cell carcinomaSemantic proximity
Development of an anoikis-related gene signature for lung squamous cell carcinoma to predict prognosis, immune landscape, and immunotherapy responseSemantic proximity
Immune-Related lncRNA Signatures Define Tumor Microenvironment Subtypes and Predict Immunotherapy Response in NSCLCSemantic proximity
Single-cell evaluation reveals innate immune arrested and lymphocytes shifting that promote development of preinvasive lung adenocarcinomaSemantic proximity
Multidimensional characterization of the tumor microenvironment profiles in lung squamous cell carcinoma.Semantic proximity
Single-cell RNA seq data analysis reveals molecular markers and possible treatment targets for Laryngeal Squamous Cell Carcinoma (LSCC): An in-silico approach.Semantic proximity
Select a neighboring publication to make it the new centre.