Article
BRAF V600E Metastatic Synovial Sarcoma Treated with BRAF & MEK Inhibitors Achieves Complete Response. A Case Report & Literature Review.
Oncology research - 1 Jan 2026
Burg Daniel, Babkoff Aryeh, Or Omer, Olshinka Noam, Demma Jonathan Abraham, Adila Mohamad, Wygoda Marc, Blumenfeld Philip, Diment Judith, Galiner Masha, Azraq Yusef, Katz Daniela, Reissman Petachia, Ostrowicki Sadie, Sebbag Gabriella, Elkhateeb Narmine, Moshe Anat Hershko, Jaber Dania, Hollander Adi, Rubin Limor, Zick Aviad
Abstract excerpt
Background: -Synovial sarcoma is a rare soft tissue sarcoma. Treatment of synovial sarcoma includes surgery, radiation, pazopanib, and chemotherapy. Targeted therapies, such as B-Raf proto-oncogene, serine/threonine kinase (BRAF) inhibitors, are emerging as a potential treatment option. We describe the sixth case of a BRAFV600E synovial sarcoma, the first extra-thoracic case. This case is the first to show a...
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