Identification of a DICER1 mutation in a preeclamptic patient with ruptured ovarian Sertoli-Leydig cell tumor and renal allograft failure under hemodialysis: a case report.

Abstract excerpt

BACKGROUND: Patients with renal allograft failure undergoing hemodialysis may be associated with an increased risk of preeclampsia. Preeclampsia can present with systemic manifestations, including organ bleeding. In this case, a suspected placental abruption was eventually confirmed to be caused by the rupture of an ovarian Sertoli–Leydig cell tumor (SLCT). A DICER1 mutation was subsequently identified in the...

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