Article
DICER1 Mutation in Recurrent Ovarian Sertoli-Leydig Cell Tumor: A Case Report.
Journal of pediatric and adolescent gynecology - 1 Apr 2023
Liu Shalon, Pokoradi Alida J, Soboleski Donald, Childs Timothy, Agrawal Anita
Abstract excerpt
BACKGROUND: DICER1 mutation has been linked to development of Sertoli-Leydig cell tumor and cystic nephroma, among other neoplasms. CASE: We present a unique case of recurrent ovarian Sertoli-Leydig cell tumor in a pediatric patient with a known DICER1 mutation and history of cystic nephroma. She underwent surgical staging and adjuvant chemotherapy, and her recurrences have been treated with chemotherapy,...
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