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Article

DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association.

The Journal of clinical endocrinology and metabolism - 1 Jan 2016

Rutter Meilan M, Jha Pranati, Schultz Kris Ann P, Sheil Amy, Harris Anne K, Bauer Andrew J, Field Amanda L, Geller James, Hill D Ashley

Abstract excerpt

CONTEXT: DICER1 germline mutation carriers have an increased predisposition to cancer, such as pleuropulmonary blastoma (PPB) and Sertoli-Leydig cell tumor (SLCT), and a high prevalence of multinodular goiter (MNG). Although differentiated thyroid carcinoma (DTC) has been reported in some DICER1 mutation carriers with PPB treated with chemotherapy, the association of DTC with DICER1 mutations is not well...

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Source

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Identifiers

PMID: 26555935
DOI: 10.1210/jc.2015-2169
PMCID: PMC4701837

Genes

DICER1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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