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Article

Computational prediction of binding affinity and structural impact of three Pakistani SARS-CoV-2 spike RBD variants on human ACE2 interaction.

PloS one - 1 Jan 2026

Usama Muhammad, Azeem Muhammad, Mustafa Ghulam

Abstract excerpt

Despite the current development and progress in vaccine synthesis, the transmission and infection rate of new variants of SARS-CoV-2 is still challenging in developing countries like Pakistan. Previous studies reported the transmission of new virus variants associated with the mutation in spike protein particularly in the receptor binding domain (RBD) of SARS-CoV-2 making RBD a promising target to control the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41920812
DOI: 10.1371/journal.pone.0346242
PMCID: PMC13042742

Genes

ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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