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Article

Computational analysis of affinity dynamics between the variants of SARS-CoV-2 spike protein (RBD) and human ACE-2 receptor.

Virology journal - 19 Apr 2024

Sultana Nishad, Nagesha S N, Reddy C N Lakshminarayana, Ramesh B N, Shyamalamma S, Shashidhara K S, Satish K M, Pradeep C, Vidyadhar G D

Abstract excerpt

The novel coronavirus SARS-CoV-2 resulted in a significant worldwide health emergency known as the COVID-19 pandemic. This crisis has been marked by the widespread of various variants, with certain ones causing notable apprehension. In this study, we harnessed computational techniques to scrutinize these Variants of Concern (VOCs), including various Omicron subvariants. Our approach involved the use of protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38641844
DOI: 10.1186/s12985-024-02365-3
PMCID: PMC11031966

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