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Article

Exosomal non-coding RNAs-mediated EGFR-TKIs resistance in NSCLC with EGFR mutation.

Medical oncology (Northwood, London, England) - 28 Jul 2023

Cheng Daoan, Wang Banglu, Wu Lige, Chen Rui, Zhao Weiqing, Fang Cheng, Ji Mei

Abstract excerpt

Lung cancer is the leading cause of cancer-related mortality worldwide. The advent of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) has significantly improved survival rates of patients with EGFR-mutant non-small cell lung cancer (NSCLC). However, as with other antitumor drugs, resistance to EGFR-TKIs is inevitably develops over time. Exosomes, extracellular vesicles with a 30-150 nm...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37505345
DOI: 10.1007/s12032-023-02125-3

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