Article
Deep transcriptome profiling of clinical Klebsiella pneumoniae isolates reveals strain and sequence type-specific adaptation.
Environmental microbiology - 1 Nov 2015
Bruchmann Sebastian, Muthukumarasamy Uthayakumar, Pohl Sarah, Preusse Matthias, Bielecka Agata, Nicolai Tanja, Hamann Isabell, Hillert Roger, Kola Axel, Gastmeier Petra, Eckweiler Denitsa, Häussler Susanne
Abstract excerpt
Health-care-associated infections by multi-drug-resistant bacteria constitute one of the greatest challenges to modern medicine. Bacterial pathogens devise various mechanisms to withstand the activity of a wide range of antimicrobial compounds, among which the acquisition of carbapenemases is one of the most concerning. In Klebsiella pneumoniae, the dissemination of the K. pneumoniae carbapenemase is tightly...
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