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Article

Locus- and Gene-Level Insights into the Inverse Association Between Alzheimer's Disease and Cancer.

International journal of molecular sciences - 23 Mar 2026

Debnath Dipti, Housini Mohammad, Sariya Sanjeev, Phillips Nicole R, Pathak Gita A, Barber Robert C

Abstract excerpt

Alzheimer's disease (AD) and cancer are both age-related conditions, yet numerous large-scale epidemiological studies have consistently documented an inverse association, with individuals diagnosed with cancer exhibiting a reduced risk of AD and vice versa. Although this relationship has been replicated across diverse populations, its biological basis remains poorly understood. To address this gap, the present...

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Identifiers

PMID: 41898760
DOI: 10.3390/ijms27062900
PMCID: PMC13026669

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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