Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics.

Human genetics - 1 Oct 2017

Feng Yen-Chen Anne, Cho Kelly, Lindstrom Sara, Kraft Peter, Cormack Jean, Liang Liming, Driver Jane A

Abstract excerpt

Growing evidence from both epidemiology and basic science suggest an inverse association between Alzheimer's disease (AD) and cancer. We examined the genetic relationship between AD and various cancer types using GWAS summary statistics from the IGAP and GAME-ON consortia. Sample size ranged from 9931 to 54,162; SNPs were imputed to the 1000 Genomes European panel. Our results based on cross-trait LD Score...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Bioinformatics and Genomic Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer-related cognitive impairment studies

Share to Ferroptosis and cancer prognosis

Share to Genome-Wide Association Study

Share to Neoplasms

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 28780673
DOI: 10.1007/s00439-017-1831-6
PMCID: PMC5693762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics.PMID 28780673Read ↗

Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer's disease risk.Semantic proximity Read ↗

Locus- and Gene-Level Insights into the Inverse Association Between Alzheimer's Disease and Cancer.Semantic proximity Read ↗

Prediction of Alzheimer’s Disease-Associated Genes by Integration of GWAS Summary Data and Expression DataSemantic proximity Read ↗

Alzheimer’s Disease variant portal (ADVP): a catalog of genetic findings for Alzheimer’s DiseaseSemantic proximity Read ↗

A <i>multiple-causal-gene-cluster</i> model underlying GWAS signals of Alzheimer’s diseaseSemantic proximity Read ↗

Cross-omic dissection reveals locus-specific heterogeneity and antagonistic pleiotropy between Alzheimer’s disease and type 2 diabetesSemantic proximity Read ↗

Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.Semantic proximity Read ↗

Shared heritability and functional enrichment across six solid cancersSemantic proximity Read ↗

Identifying Alzheimer’s disease-related pathways based on whole-genome sequencing dataSemantic proximity Read ↗

Shared heritability and functional enrichment across six solid cancers.Semantic proximity Read ↗

Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer.Semantic proximity Read ↗

A gene-level methylome-wide association analysis identifies novel Alzheimer’s disease genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.