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Article

Causal relationship between genetically predicted Enzyme and Tinnitus risk: a two-sample bi-directional mendelian randomization study.

Brazilian journal of otorhinolaryngology - 1 Jan 2026

Liu Peng, Xue Xinmiao, Zhang Zhixin, Zhang Lijun, Peng Yu, Song Qi, Wang Fangyuan

Abstract excerpt

OBJECTIVES: Observational studies have reported an association between enzymes and tinnitus. However, the exact nature and strength of the causal relationship between enzymes and tinnitus remain unclear. METHODS: In this study, we utilized two-sample bi-directional mendelian randomization using publicly available GWAS summary statistics to investigate the causal relationship between enzymes and the risk of...

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Share to Enzymes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 41895103
DOI: 10.1016/j.bjorl.2026.101804
PMCID: PMC13058955

Genes

ATG7
DTX1
FKBP6
MID2
ZNRF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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