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Article

The Causal Relationship Between Circulating Inflammatory Proteins and Tinnitus: A Mendelian Randomization Study Mediated by Blood Metabolites

1 Sept 2025

Abstract excerpt

PURPOSE: Tinnitus is a complex disease whose pathophysiological mechanisms are still not fully elucidated. Dysregulation of circulating inflammatory proteins and metabolites is thought to play a crucial role in tinnitus pathophysiology, but the causal relationships and specific biological pathways linking these factors to tinnitus persistence remain unestablished. METHODS: We performed a two-sample Mendelian...

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Identifiers

PMID: 40898658
DOI: 10.1002/brb3.70699

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