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Article

Clinicopathological Study of a Series of Melanomas With IDH1 Mutation.

The American Journal of dermatopathology - 1 Aug 2026

Carbonell-Zamorano Javier, Santonja-López Nuria, Navarro Lara, Fernandez Amaya, Calabuig-Fariñas Silvia, Sabater-Marco Vicente

Abstract excerpt

ABSTRACT: Isocitrate dehydrogenase 1 (IDH1) mutations are well-established oncogenic drivers in several malignancies, including gliomas and hematologic neoplasms, but are rarely reported in melanoma and remain poorly characterized in this tumor type. Their clinicopathological and molecular significance in cutaneous melanoma is not well-defined. We retrospectively analyzed 9 cases of cutaneous melanoma harboring...

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Source

Identifiers

PMID: 41894668
DOI: 10.1097/DAD.0000000000003272

Genes

IDH1
PRAME
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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