Article
Causality between rheumatic diseases and iron-deficiency anemia: A 2-sample, 2-step mediation Mendelian randomization investigation.
Medicine - 5 Dec 2025
Huang Wei, Lv Luyao, Zhang Yaqi, Jin Tianyu, Cheng Yifan, Geng Linyu, Feng Xuebing
Abstract excerpt
Growing evidence suggests that patients with rheumatic disease are associated with iron-deficiency anemia (IDA). However, the causal relationship between rheumatic disease and IDA risk remains unclear. To investigate this, we conducted a Mendelian randomization (MR) study using genetic variants from the large genome-wide association studies. In this study, we primarily investigated common rheumatic diseases,...
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