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Article

Cumulative effects of mutation and selection on susceptibility to bacterial pathogens in Caenorhabditis elegans.

Evolution; international journal of organic evolution - 17 Oct 2025

Saber Sayran, Johnson Lindsay M, Rifat Md Monjurul Islam, Rouse Sidney, Baer Charles F

Abstract excerpt

Understanding the evolutionary and genetic underpinnings of susceptibility to pathogens is of fundamental importance across a wide swathe of biology. Much theoretical and empirical effort has focused on genetic variants of large effect, but pathogen susceptibility often appears to be a polygenic complex trait. Here, we investigate the quantitative genetics of survival over 120 h of exposure ("susceptibility") of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40515768
DOI: 10.1093/evolut/qpaf132
PMCID: PMC12533481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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