Article
Cumulative effects of spontaneous mutations for fitness in Caenorhabditis: role of genotype, environment and stress.
Genetics - 1 Nov 2006
Baer Charles F, Phillips Naomi, Ostrow Dejerianne, Avalos Arián, Blanton Dustin, Boggs Ashley, Keller Thomas, Levy Laura, Mezerhane Edward
Abstract excerpt
It is often assumed that the mutation rate is an evolutionarily optimized property of a taxon. The relevant mutation rate is for mutations that affect fitness, U, but the strength of selection on the mutation rate depends on the average effect of a mutation. Determination of U is complicated by t...
Topics
- Animals
- Caenorhabditis
- Environment
- Genotype
- Mutation
- Species Specificity
- Stress, Physiological
- Temperature