Article
SNTB1 gene polymorphisms and risk of high myopia: meta-analysis and single-center validation.
Molecular vision - 1 Jan 2025
Peng Jie, Wang Yina, Lu Jiaqing, Wang Ying, Dong Yongning, Fang Jie, Chen Xu
Abstract excerpt
Purpose: Genetic polymorphisms in syntrophin beta-1 (SNTB1) have been implicated in altering protein function or expression, potentially influencing ocular growth regulation. Genome-wide association studies (GWASs) suggest that specific SNTB1 variants may correlate with high myopia susceptibility across diverse populations. However, findings remain inconsistent, highlighting the need for further investigation...
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