Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subtype-specific APOBEC enrichment links genomic instability to predict immunotherapy response in breast cancer subtypes.

International journal of biological macromolecules - 1 Apr 2026

Zhao ZeWei, Zhou JiaQi, Jia WenBin, Xie Yongjie, Zhou Yaoyao, Ning ChunLan, Cao XuChen, Yu Yue, Wang Xin

Abstract excerpt

Breast cancer (BRCA), a prevalent malignancy among women, significantly impacts survival quality and life expectancy, with rising incidence and mortality rates posing substantial psychological and economic burdens on patients and families. Current treatment modalities exhibit considerable variability in efficacy, often hindered by resistance and recurrence, thus emphasizing the urgent need for novel biomarkers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APOBEC Deaminases
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Genomic Instability

Share to Immunotherapy

Share to Mutation

Share to Prognosis

Source

Identifiers

PMID: 41865932
DOI: 10.1016/j.ijbiomac.2026.151525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subtype-specific APOBEC enrichment links genomic instability to predict immunotherapy response in breast cancer subtypes.PMID 41865932Read ↗

APOBEC in breast cancer: a dual player in tumor evolution and therapeutic responseSemantic proximity Read ↗

Mutation burden-orthogonal tumor genomic subtypes delineate responses to immune checkpoint therapySemantic proximity Read ↗

Delineation of the heterogeneity underlying genomic instability in hereditary breast cancers reveals four disease subtypes.Semantic proximity Read ↗

Mutation burden-orthogonal tumor genomic subtypes delineate responses to immune checkpoint therapy.Semantic proximity Read ↗

APOBEC3 mutagenesis drives therapy resistance in breast cancerSemantic proximity Read ↗

Integrative genomic analyses of APOBEC-mutational signature, expression and germline deletion of APOBEC3 genes, and immunogenicity in multiple cancer typesSemantic proximity Read ↗

The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers.Semantic proximity Read ↗

Uncovering the Subtype-Specific Molecular Characteristics of Breast Cancer by Multiomics Analysis of Prognosis-Associated Genes, Driver Genes, Signaling Pathways, and Immune ActivitySemantic proximity Read ↗

Predictors of Chemosensitivity in Triple Negative Breast Cancer: An Integrated Genomic AnalysisSemantic proximity Read ↗

Durable Complete Response With Immune Checkpoint Inhibitor in Breast Cancer With High Tumor Mutational Burden and APOBEC Signature.Semantic proximity Read ↗

APOBEC3B mRNA Expression in Breast Cancer Correlates with Genomic Mutational SignaturesSemantic proximity Read ↗

APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell-Mediated Antitumor Immune Responses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.