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Distinct Behavioral Roles of D-Aspartate Oxidases DDO-1 and DDO-2 in Caenorhabditis elegans.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Mar 2026

Saitoh Yasuaki, Katane Masumi, Miyamoto Tetsuya, Sekine Masae, Homma Hiroshi

Abstract excerpt

D-amino acids are widely distributed across organisms, and their metabolism contributes to the regulation of neuronal activity and behavior. Whereas most animals possess one D-amino acid oxidase (DAAO) for neutral and basic D-amino acids and one D-aspartate oxidase (DDO) for acidic D-amino acids, the nematode Caenorhabditis elegans uniquely carries three DDOs. Previous studies showed that DDO-3 affects the nose...

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PMID: 41863028
DOI: 10.1111/gtc.70103

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DDO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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