Article
An SLC6 transporter of the novel B(0,)- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans.
The Journal of experimental biology - 1 Aug 2013
Metzler Ryan, Meleshkevitch Ella A, Fox Jeffrey, Kim Hongkyun, Boudko Dmitri Y
Abstract excerpt
Nutrient amino acid transporters (NATs) of solute carrier family 6 (SLC6) mediate uptake of essential amino acids in mammals and insects. Phylogenomic analysis of the Caenorhabditis elegans (Ce) SLC6 family identifies five genes paralogous to an insect-specific NAT subfamily. Here we cloned and characterized the first representative of the identified nematode-specific transporters, SNF-5. SNF-5 mediates broad...
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