Statistical models to characterize colon tumor stiffness heterogeneity through representative atomic force microscopy maps.

Abstract excerpt

The study of the impact of physical forces and on cells has emerged as a fertile field of investigation. Applications in oncology are especially transformative since tumor stiffness was found associated with fundamental processes such as tumorigenicity, disease progression, and resistance to therapy. We present an integrated atomic force microscopy-statistical modeling and machine learning approach in colon...

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