Article
Genetics of skeletal proportions across two different populations.
American journal of human genetics - 2 Apr 2026
Bartell Eric, Lin Kuang, Tsuo Kristin, Gan Wei, Vedantam Sailaja, Cole Joanne B, Baronas John M, Yengo Loic, Marouli Eirini, Amariuta Tiffany, Chen Zhengming, Li Liming, Renthal Nora E, Jacobsen Christina M, Salem Rany M, Walters Robin G, Hirschhorn Joel N
Abstract excerpt
Human height can be divided into sitting height and leg length. These measures reflect the growth of different parts of the skeleton whose relative proportions are captured by the ratio of sitting to total height (the sitting height ratio [SHR]). Height is a highly heritable trait, and its genetic basis has been well studied. However, the genetic determinants of skeletal proportion are much less well...
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