Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HRPU-2, a Homolog of Mammalian hnRNP U, Regulates Synaptic Transmission by Controlling the Expression of SLO-2 Potassium Channel in Caenorhabditis elegans.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 31 Jan 2018

Liu Ping, Wang Sijie Jason, Wang Zhao-Wen, Chen Bojun

Abstract excerpt

Slo2 channels are large-conductance potassium channels abundantly expressed in the nervous system. However, it is unclear how their expression level in neurons is regulated. Here we report that HRPU-2, an RNA-binding protein homologous to mammalian heterogeneous nuclear ribonucleoprotein U (hnRNP U), plays an important role in regulating the expression of SLO-2 (a homolog of mammalian Slo2) in Caenorhabditis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caenorhabditis elegans Proteins

Share to Epilepsy

Share to Intellectual Disability

Share to Motor Activity

Share to Motor Neurons

Share to Synaptic Transmission

Source

Open in PubMed Open full text

Identifiers

PMID: 29217678
DOI: 10.1523/JNEUROSCI.1991-17.2017
PMCID: PMC5792471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HRPU-2, a Homolog of Mammalian hnRNP U, Regulates Synaptic Transmission by Controlling the Expression of SLO-2 Potassium Channel in Caenorhabditis elegans.PMID 29217678Read ↗

A scaffold attachment factor PHM-2 regulates synaptic transmission through SLO-2 potassium channel in <i>C. elegans</i>Semantic proximity Read ↗

A scaffold attachment factor PHM-2 regulates synaptic transmission through SLO-2 potassium channel in C. elegans.Semantic proximity Read ↗

Slo2 potassium channel function depends on a SCYL1 proteinSemantic proximity Read ↗

HRP-2, a heterogeneous nuclear ribonucleoprotein, is essential for embryogenesis and oogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

The Liprin homology domain is essential for the homomeric interaction of SYD-2/Liprin-α protein in presynaptic assembly.Semantic proximity Read ↗

Systematic analyses of rpm-1 suppressors reveal roles for ESS-2 in mRNA splicing in Caenorhabditis elegans.Semantic proximity Read ↗

The Caenorhabditis elegans ekl (enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway.Semantic proximity Read ↗

The RNA binding KH domain of Spoonbill depletes pathogenic non-coding spinocerebellar ataxia 8 transcripts and suppresses neurodegeneration in Drosophila.Semantic proximity Read ↗

Natural variations in small RNA origin loci generate circuit diversity underlying temperature acclimation in Caenorhabditis elegans.Semantic proximity Read ↗

Control of rapsyn stability by the CUL-3-containing E3 ligase complex.Semantic proximity Read ↗

Dystrobrevin controls neurotransmitter release and muscle Ca(2+) transients by localizing BK channels in Caenorhabditis elegans.Semantic proximity Read ↗

Mutations in the hrp48 gene, which encodes a Drosophila heterogeneous nuclear ribonucleoprotein particle protein, cause lethality and developmental defects and affect P-element third-intron splicing in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.