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Genetics of BAG3: A Paradigm for Developing Precision Therapies for Dilated Cardiomyopathies

16 Nov 2022

Abstract excerpt

Nonischemic dilated cardiomyopathy is a common form of heart muscle disease in which genetic factors play a critical etiological role. In this regard, both rare disease‐causing mutations and common disease‐susceptible variants, in the Bcl‐2–associated athanogene 3 ( BAG3 ) gene have been reported, highlighting the critical role of BAG3 in cardiomyocytes and in the development of dilated cardiomyopathy. The...

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PMID: 36382946
DOI: 10.1161/jaha.122.027373

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Genetics of BAG3: A Paradigm for Developing Precision Therapies for Dilated CardiomyopathiesPMID 36382946Read ↗

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