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Assessment of MIR3142HG genetic polymorphisms and the susceptibility of lumbar disc herniation in the Chinese population.

Scientific reports - 28 Nov 2024

Dong Qi, Ren Guoxia, Hao Dingjun

Abstract excerpt

Lumbar disc herniation (LDH) is a common degenerative disease of the lumbar spine, which is related to host genetic factors. Our study aimed to explore the association between MIR3142HG polymorphisms and LDH susceptibility. Six SNPs in MIR3142HG from 504 LDH patients and 500 healthy individuals were genotyped by the Agena MassARRAY platform. The relationship between SNPs and LDH susceptibility was evaluated with...

Topics

Adult
Aged
Female
Humans
Male
Middle Aged
Case-Control Studies
China
East Asian People
Genetic Predisposition to Disease
Genotype
Intervertebral Disc Displacement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lumbar Vertebrae

MicroRNAs

Polymorphism, Single Nucleotide

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Open in PubMed Open full text

Identifiers

PMID: 39604548
DOI: 10.1038/s41598-024-80758-8
PMCID: PMC11603262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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