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Article

Comprehensive molecular-clinical profiling of cholangiocarcinoma according to pathologic subtypes.

HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 Jun 2026

Ahn Keun Soo, O'Brien Daniel, Kang Yoo Na, Mounajjed Taofic, Lee Hye Won, Kim Yong Hoon, Kim Tae-Seok, Kim Min Jae, Han Jin-Yi, Borad Mitesh J, Roberts Lewis R

Abstract excerpt

BACKGROUND: Pathologically, cholangiocarcinoma (CCA) can be classified into small duct type and large duct type. This study evaluated clinical and molecular features of CCA according to its pathological subtype. METHODS: We analyzed 107 patients with CCA from three independent cohorts who underwent curative surgical resection. Clinical data, gene expression profiles, and mutation status were compared between...

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Identifiers

PMID: 41850925
DOI: 10.1016/j.hpb.2026.02.007

Genes

KRAS
FGFR2
IDH1
PIK3CA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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