Article
An approach to identifying drug resistance associated mutations in bacterial strains.
BMC genomics - 1 Jan 2012
Wozniak Michal, Tiuryn Jerzy, Wong Limsoon
Abstract excerpt
BACKGROUND: Drug resistance in bacterial pathogens is an increasing problem, which stimulates research. However, our understanding of drug resistance mechanisms remains incomplete. Fortunately, the fast-growing number of fully sequenced bacterial strains now enables us to develop new methods to identify mutations associated with drug resistance. RESULTS: We present a new comparative approach to identify genes and...
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