Article
Genomic sequencing of multicystic mesothelioma finds cohesin complex mutations associated with disease recurrence in patients referred for cytoreductive surgery and HIPEC.
British journal of cancer - 1 May 2026
Gibson Jane, Carr Norman John, Stanford Sophia, Mirandari Amatta, Cecil Thomas Desmond, Pengelly Reuben J, Turner Steven, Essex Jonathan W, Boukas Konstantinos, Hocking Kevin, Dominguez Manuel, Mohamed Faheez, Dayal Sanjeev Paul, Tzivanakis Alexios, Moran Brendan John, Adeleke Gbadebo, Mirnezami Alex, Ennis Sarah
Abstract excerpt
BACKGROUND: Multicystic mesothelioma (MCM) is a rare disease and there is debate about it's neoplastic nature with a spectrum of disease behaviour and little known about the genomic profile. In contrast, the genomic profile of malignant peritoneal mesothelioma (MPeM) is characterised. METHODS: We characterized 24 MCM and 18 MPeM cases across a panel of cancer related regions and expanded to whole-exome sequencing...
Topics
Join the communities discussing this publication.