Article
Machine learning -driven discovery of Parkinsonian-like phenotypes in idiopathic REM sleep behavior disorder.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 13 Mar 2026
Giardino D L, Huck-Iriart C, Gonzalez P M, Aguirre P A, Fededa J P, Peralta C, Valiensi S M, Garay A
Abstract excerpt
INTRODUCTION: This study harnessed AI-powered tools like principal component analysis (PCA) and multivariate models (PCA-MV) to integrate clinical and laboratory data from Parkinson’s disease (PD) patients, individuals with idiopathic REM sleep behavior disorder (iRBD), and healthy controls. The aim was to identify phenotypic similarities between iRBD and PD and to explore subgroup patterns within the iRBD...
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