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Article

Ageing phenotypes and behavioural determinants of health on age acceleration: the Cancer Survivors' Trajectories of Ageing Research (C*STAR) study protocol.

BMJ open - 12 Mar 2026

Zaujan Nur Afifah Mursyida, Shahril Mohd Razif, Shahar Suzana, Mohamad Hanif Ezanee Azlina, Ab Muin Nur Fa'izah, Sharif Razinah, Subramaniam Ponnusamy, Abdullah Azizi, Fenech Michael

Abstract excerpt

INTRODUCTION: Age acceleration in survivors of breast cancer is a critical issue because cancer and its treatment can increase structural and numerical chromosomal aberrations, while simultaneously shortening telomere length and changing ageing phenotype. Therefore, the current study will be using machine learning architectures to accurately predict the factors that contribute to age acceleration among survivors...

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Identifiers

PMID: 41819575
DOI: 10.1136/bmjopen-2025-102594
PMCID: PMC12993301

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