The genetic support for the causal relationship between 91 circulating inflammatory proteins and pneumothorax: A two-sample mendelian randomization study.

doi:10.1016/j.hrtlng.2025.09.001

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Article

The genetic support for the causal relationship between 91 circulating inflammatory proteins and pneumothorax: A two-sample mendelian randomization study.

Heart & lung : the journal of critical care - 1 Jan 2026

Zhou Changshuai, Zhang Ran

Abstract excerpt

BACKGROUND: Pneumothorax, a common pleural disease, has an unclear pathogenesis. Observational studies suggest that inflammation may directly or indirectly contribute to the development of pneumothorax. OBJECTIVES: To investigate the causal relationship between circulating inflammatory proteins and pneumothorax using Mendelian randomization (MR) analysis. METHODS: We conducted a two-sample Mendelian randomization...

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PMID: 40930056
DOI: 10.1016/j.hrtlng.2025.09.001

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SIRT2
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