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Article

Mutations in Exon 29 of Ring Finger Protein 213 Are Associated with Early-Onset Colorectal Cancer.

Digestive diseases and sciences - 1 Aug 2026

Jiang Enoch Xun, Quarta Giulio, Delau Olivia, Shaukat Aasma

Abstract excerpt

BACKGROUND AND AIMS: Growing evidence suggests that the gut microbiome plays a role in carcinogenesis for early-onset colorectal cancer (EOCRC). The novel Ring Finger Protein 213 (RNF213) gene has broad antimicrobial properties. Our study aimed to compare RNF213 mutation rates in EOCRC and late-onset colorectal cancer using data from the cBioPortal for Cancer Genomics. METHODS: All participants from the...

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Identifiers

PMID: 41787031
DOI: 10.1007/s10620-026-09784-y

Genes

RNF213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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