Article
Comparison of single-cell sequencing technologies for allele-specific expression analysis in rabbit spermatids.
Genomics - 1 May 2026
Smertina Elena, Rutherford Madi, Hosking Brendan, Kargarfard Nehleh, Wilson Laurence O W, Oh Kevin P, Smith Ina L, Strive Tanja, Jenckel Maria
Abstract excerpt
Gene drives are transmission distorters that can transmit specific alleles to >90% of the progeny, e.g., the naturally occurring t-haplotype in mice. The hypothesised mechanism involves biased allele expression with impaired transcript sharing between developing spermatids. For invasive pest species, there is interest in co-opting naturally occurring gene drives. It is unknown whether similar natural gene drives...
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