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Article

A single mutation in nonstructural protein 1 is critical for the adaptive evolution of influenza B virus.

Nature communications - 2 Mar 2026

Jiao Pengtao, Jia Xiaoxiao, Bai Xiaoyuan, Zhao Yuna, Lin Runshan, Fan Zeqiu, Fan Wenhui, Zhang He, Li Heqiao, Bi Yuhai, Wang Dayan, Liu Wenjun, Sun Lei

Abstract excerpt

Influenza B virus (IBV) has circulated in the human population for a long time, yet the evolutionary mechanisms responsible for host adaptation remain poorly understood. Here we show that recent IBV strains exhibit an enhanced ability to evade the innate immune response and an increased replication efficiency compared with earlier strains. Our data indicate that the nonstructural protein 1 (NS1) of recent IBV...

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Identifiers

PMID: 41771888
DOI: 10.1038/s41467-026-70211-x
PMCID: PMC13066462

Genes

MAVS
TUFM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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