Article
Molecular Profiling of Cholangiocarcinoma Predicts Outcomes Post-Liver Transplantation.
JCO precision oncology - 1 Mar 2026
Connor Ashton A, Mattohti Mahinur, Kodali Sudha, Abdelrahim Maen, Elaileh Ahmed, Semaan Samar, Mobley Constance M, Simon Caroline J, Cheah Yee Lee, Saharia Ashish, Dhingra Sadhna, Schwartz Mary R, Moore Linda W, Heyne Kirk, Victor David W, Li Xian C, Vauthey Jean-Nicolas, Javle Milind, Gaber A Osama, Ghobrial R Mark
Abstract excerpt
PURPOSE: Cholangiocarcinoma (CCA) has rising incidence and mortality rates. Liver transplantation (LT) offers good outcomes. Tumor molecular profiling may inform peri-LT treatment. MATERIALS AND METHODS: Patients with CCA who underwent LT at a single center between 2014 and 2021 were identified retrospectively. Next-generation sequencing (277 genes) was performed on 28 CCAs from 18 patients, including five...
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