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Article

Impact of MEFV mutations on inflammatory activity and long-term relapse in pediatric IgA vasculitis.

BMC pediatrics - 27 Feb 2026

Özdemir Göktuğ, Özdemir Esma Kaya, Gültekin Asım

Abstract excerpt

BACKGROUND: IgA vasculitis (IgAV) is the most common childhood small-vessel vasculitis. MEFV variants may enhance innate inflammatory responses, but their effect on disease course remains unclear. OBJECTIVES: To determine the prevalence of MEFV mutations in pediatric IgAV and evaluate associations with inflammatory activity and long-term outcomes. METHODS: In this retrospective cohort study, 62 children with IgAV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41761137
DOI: 10.1186/s12887-026-06664-2
PMCID: PMC13049734

Genes

MEFV
CRP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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