Childhood-Onset ANCA-Associated Vasculitis: From Genetic Studies to Advances in Pathogenesis, Classification and Novel Therapeutic Approaches.

Abstract excerpt

Childhood-onset antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) represents a heterogeneous group of multi-system autoimmune conditions associated with chronic inflammation, characteristically affecting small blood vessels, leading to various organ and system manifestations. Although rare in paediatric populations, AAV poses challenges in early recognition, diagnosis and management of...

Topics

Join the communities discussing this publication.

• Age of Onset
• Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
• Antibodies, Antineutrophil Cytoplasmic
• Child
• Coagulation, Bradykinin, Polyphosphates, and Angioedema