Article

Impact of MEFV Mutations on Inflammatory Activity and Long-Term Relapse in Pediatric IgA Vasculitis

2026-02-03

Abstract excerpt

<title>Abstract</title> <p>Background IgA vasculitis (IgAV), formerly Henoch–Schönlein purpura, is the most common systemic vasculitis of childhood. MEFV mutations have been linked to enhanced inflammatory responses and vasculitis, although their impact on long-term outcomes remains unclear. Objectives To determine the prevalence of MEFV mutations in children with IgAV and to evaluate their associations with cl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 59808193-ea25-552f-9785-9b14f643229d
DOI: 10.21203/rs.3.rs-8599952/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Impact of MEFV Mutations on Inflammatory Activity and Long-Term Relapse in Pediatric IgA VasculitisDOI 10.21203/rs.3.rs-8599952/v1Read

Impact of MEFV mutations on inflammatory activity and long-term relapse in pediatric IgA vasculitis.Semantic proximity Read

Genetics of IgA Vasculitis: What We Know and Where We Are Going.Semantic proximity Read

IgA Vasculitis: Genetics and Clinical and Therapeutic Management.Semantic proximity Read

Clinical spectrum of pediatric patients carrying heterozygous MEFV gene variants.Semantic proximity Read

Clinical characteristics of immunoglobulin A vasculitis associated with the Mediterranean fever gene mutation in Japanese patients: a case-based literature reviewSemantic proximity Read

MEFV gene variants in children with Henoch-Schönlein purpura and association with clinical manifestations: a single-center Mediterranean experienceSemantic proximity Read

Impact of aging on phenotype and prognosis in IgA vasculitis.Semantic proximity Read

Clinical phenotype and cytokine profile of adult IgA vasculitis with joint involvement.Semantic proximity Read

Advances in childhood vasculitis.Semantic proximity Read

Childhood-Onset ANCA-Associated Vasculitis: From Genetic Studies to Advances in Pathogenesis, Classification and Novel Therapeutic Approaches.Semantic proximity Read

Genome-wide studies define new genetic mechanisms of IgA vasculitisSemantic proximity Read

Clinical features and the impact of MEFV Variants in pediatric non-infectious uveitis: a retrospective single-center study.Semantic proximity Read