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Article

Single-cell profiling of paired nasal brushing and tissue samples reveals distinct cellular landscapes and immune phenotypes.

The Journal of allergy and clinical immunology - 1 Jul 2026

Kim Gyeongyeob, Lee Sol, Koo Min-Seok, Moon Sungmin, Kim Dachan, Cho Hyung-Ju, Kim Chang-Hoon, Rha Min-Seok

Abstract excerpt

BACKGROUND: Since the coronavirus disease 2019 pandemic, local immune responses in the nasal mucosa have become an area of growing research interest. In this context, studies using noninvasive nasal brushing (NB) samples have increased markedly. However, it remains unclear whether NB samples accurately reflect the immune landscape of the nasal tissue (NT). OBJECTIVE: A study was conducted to directly compare the...

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Identifiers

PMID: 41759750
DOI: 10.1016/j.jaci.2026.02.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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