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Article

Strong correlation between air-liquid interface cultures and in vivo transcriptomics of nasal brush biopsy

1 Apr 2020

Abstract excerpt

Air-liquid interface (ALI) cultures are ex vivo models that are used extensively to study the epithelium of patients with chronic respiratory diseases. However, the in vitro conditions impose a milieu different from that encountered in the patient in vivo, and the degree to which this alters gene expression remains unclear. In this study we employed RNA sequencing to compare the transcriptome of fresh brushings...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32233789
DOI: 10.1152/ajplung.00050.2020

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