Article
Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma.
Mucosal immunology - 1 Apr 2026
Rahimi Rod A, Smith Neal P, Selle Amandine, Best Roya, Martin Sidney, Tuttle Elizabeth, Said Wamia, Samanta Nandini, Ling Morris F, Medoff Benjamin D, Villani Alexanda-Chloé, Luster Andrew D
Abstract excerpt
T cells play a central role in host protection against respiratory pathogens, but a maladaptive T cell response can lead to pulmonary diseases. Previous studies have examined T cells from the lungs captured via bronchoalveolar lavage (BAL), endobronchial brushings, or biopsies. However, whether these different approaches are capturing distinct T cell phenotypes and/or clonotypes remains unclear. Here, using...
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