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Article

Programmed cell death and risk of diabetic retinopathy: a Mendelian randomization study.

Journal of translational medicine - 26 Feb 2026

Chen Yingying, Xu Hanyi, Wei Hengguang, Zhao Rupeng, Tan Yufen, Lin Huiying, Li Na

Abstract excerpt

BACKGROUND: Programmed cell death (PCD) plays an important role in diabetic retinopathy (DR); however, the underlying genetic mechanisms remain unclear. We used Mendelian randomization (MR) to investigate the causal relationships between PCD-related genes and DR. This study aimed to investigate the effects of PCD on the risk of DR by conducting MR analysis. METHODS: Summary statistics from gene expression...

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Share to Bayes Theorem
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 41749353
DOI: 10.1186/s12967-026-07921-9
PMCID: PMC13041394

Genes

CTSH
PGAM5
TNF
NQO1
TRIB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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