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Identification of macrophage polarisation and mitochondria-related biomarkers in diabetic retinopathy

6 Jan 2025

Abstract excerpt

BACKGROUND: The activation of macrophages or microglia in patients' whole body or local eyes play significant roles in diabetic retinopathy (DR). Mitochondrial function regulates the inflammatory polarization of macrophages. Therefore, the common mechanism of mitochondrial related genes (MRGs) and macrophage polarisation related genes (MPRGs) in DR is explored in our study to illustrate the pathophysiology of DR....

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PMID: 39762849
DOI: 10.1186/s12967-024-06038-1

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