Rapid Forensic DNA Profiling via Real-Time Recombinase Polymerase Amplification of InDel Markers.

Abstract excerpt

Forensic DNA profiling commonly relies on polymerase chain reaction (PCR) amplification followed by capillary electrophoresis (CE) or massively parallel sequencing (MPS), which requires expensive, laboratory-based equipment that depends on a stable power supply and is unsuitable for field applications. Here, we present a proof-of-concept assay that uses recombinase polymerase amplification (RPA) combined with exo...

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• DNA
• DNA Fingerprinting
• Forensic Genetics
• Genotype
• INDEL Mutation