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Development and forensic evaluation of an 8-dye Multi-InDel multiplex panel for highly degraded samples.

Forensic science international - 1 Aug 2026

Jia Hongtao, Jiang Bowei, Wang Feng, Wang Yuepeng, Fu Xiaoyi, Liang Bin, Qu Weifeng, Liu Yi, Liu Lian, Xie Qiheng, Zheng Feifei, Wen Dan, Tang Xuan, Zha Lagabaiyila, Li Jienan

Abstract excerpt

The analysis of highly degraded DNA samples remains a significant challenge in forensic genetics. Multi-InDel present several advantages-including high polymorphisms, short amplicons, low mutation rates, and the absence of stutter artifacts-making it an ideal genetic marker for genotyping highly degraded samples. Conventional 5-dye systems commonly used for highly degraded samples often accommodate only a limited...

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DNA Degradation, Necrotic
DNA Fingerprinting
Fluorescent Dyes
Genetic Markers
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Repeats

Multiplex Polymerase Chain Reaction

Polymerase Chain Reaction

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PMID: 41967271
DOI: 10.1016/j.forsciint.2026.112962

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CPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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