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Article

Estrogen Receptor, GATA-3, TTF-1, and KRAS in Endometrial Carcinoma of No Specific Molecular Profile: Prognostic or Diagnostic Markers?

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2026

Siili Emma, Loukovaara Mikko, Bützow Ralf, Pasanen Annukka

Abstract excerpt

Endometrial carcinoma with no specific molecular profile (NSMP) is a clinicopathologically heterogeneous group of diseases with an overall intermediate prognosis. Prognostic refinement is needed for better personalized treatment. The updated European Society of Gynecological Oncology-European Society for Radiotherapy and Oncology-European Society of Pathology guidelines for endometrial carcinoma stratify NSMP...

Topics

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DNA Polymerase II
Endometrial Neoplasms
GATA3 Transcription Factor
Immunohistochemistry
Poly-ADP-Ribose Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins p21(ras)

Receptors, Estrogen

Thyroid Nuclear Factor 1

Source

Identifiers

PMID: 41713573
DOI: 10.1016/j.modpat.2026.100978

Genes

KRAS
GATA3
TTF1
POLE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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