Article
Unveiling the whole-brain impact of diffuse midline glioma: cortical morphological remodeling and network alterations driven by H3 K27 mutation.
Neuroradiology - 1 May 2026
Chen Di, Zhang Simin, Zhang Dian, Yang Yuan, Yang Xibiao, Deng Yujiao, Chen Ni, Liu Yanhui, Yue Qiang
Abstract excerpt
PURPOSE: Systemic infiltration is a hallmark pathological feature of diffuse midline glioma (DMG), which may induce subtle alterations in cortical morphology. This study sought to characterize how the normal-appearing cortex is affected by the DMG, further hypothesizing that highly aggressive “DMG, H3 K27-altered” (DMG-A) would induce greater abnormalities than “DMG, H3 K27 wild-type” (DMG-W). METHODS: Fifty-five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.